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Example sentences for: ess

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Prior to study initiation, the ESS40011 study protocol was approved by the Institutional Review Boards at each participating study site.
It was lower in magnitude than the CD4+ cell count increases reported for APV600/RTV arm at 24 weeks in antiretroviral-experienced patients in ESS40006 [ 20 ] , and similar to that reported in heavily pre-treated patients by Katlama et al [ 21 ] in a patient population with comparable baseline disease characteristics (median HIV-1 RNA of 4.5 log 10 /mL and CD4+ count of 227 cells/mm 3).
In a recent large-scale screen with 1739 yeast proteins used as bait [ 3 ] , midasin (YLR106p) was identified in the polypeptide sets that copurified with four bait proteins, ESS1p, RPT1p, YML029p and HRT1p, that function principally in RNA metabolism and in the regulation of proteasomes (which are mostly intranuclear in yeast [ 50 ] ). However, the interpretation of these proteomic data is clouded by the fact that no protein partners were identified in the complementary experiment in which midasin was itself used as bait.
Thus, plasma APV levels well above the IC 50 s of most HIV isolates were most likely achieved in ESS40011.
However, ESS40006, which also evaluated the APV600/RTV regimen over a 24-week period, did conduct a pharmacokinetic evaluation showing steady-state serum APV C min values of 2.49 μg/mL (i.e.