Words similar to ers
Example sentences for: ers
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In situ hybridization and immunolocalization of ERα and ERβ in a variety of reproductive tract tissues in males and females have shown that in most instances either ERα or ERβ is expressed in a particular cell type, although some cell types, e.g., Leydig cells, ovarian surface epithelium, and epithelial and stromal cells of the uterus and breast, may show expression of both ERs [ 39 40 41 ] . However, since only a proportion of cells were detected to express ERα or ERβ in a single color immunohistochemistry [ 42 ] , such an approach cannot demonstrate coexpression of the ERs in a particular cell, nor indicate eventual transition from one ER subtype to another during differentiation.
ERα enhances AP-1 activity in response to estrogens, [ 28 29 ] but ERβ inhibits AP-1 activity in response to estrogens [ 29 30 31 ] . ERβ also completely suppresses ERα activity at the cyclin D1 promoter and even suppresses the activity of an ERα mutant that is selectively superactive at AP-1 sites and CREs [ 29 ] . Finally, ERβ shows a unique capacity to enhance AP-1 activity in response to selective estrogen receptor modulators (SERMs) such as raloxifene, tamoxifen and ICI 182,780/Faslodex (ICI) [ 30 31 32 ] . Together, these observations suggest that there are fundamental differences in the way that the ERs bind unspecified cofactors that modulate gene expression, and that some of these cofactors must play a role in differential ER activity at AP-1 sites.
However, it has to be considered that ERs are certainly not the only proteins which are involved in decisions of estrogen-dependent cells to proliferate or differentiate.
However, CT cells merging with ST and young syncytial aggregates showed expression of both ERs.
The San Diego Chargers, the Oakland Raiders, and the San Francisco 49ers all have large and faithful followings.