Example sentences for: ers

How can you use “ers” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, TSA also equalized the relative transcriptional activity of both ERs.

  • Both ERs enhance transcription from genes with classical estrogen response elements (EREs), but ERα requires less ligand to obtain maximal activation than ERβ [ 25 26 ] . Likewise, both ERs suppress the activity of the TNFα promoter in response to estrogens, but ERβ is a more potent repressor than ERα [ 27 ] . However, some of the most striking isoform-specific differences in gene regulation are observed at promoters, such as that of cyclin D1, which contain AP-1 sites or related cyclic AMP response elements (CREs).

  • Since trophoblast differentiation is associated with transition from ERα to ERβ expression, with temporary co-expression of both, one may assume that both ERs are involved in estrogen stimulated trophoblast differentiation.

  • We used ERα/ERβ dual color immunohistochemistry for co-localization of both ERs.

  • However, it has to be considered that ERs are certainly not the only proteins which are involved in decisions of estrogen-dependent cells to proliferate or differentiate.


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