Words similar to erf
Example sentences for: erf
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Rad52 functions in conjunction with the RecA ortholog, the RAD51 recombinase in double-strand break repair and meiotic recombination [ 6 ] . RAD52 binds ssDNA during recombination and also shows a quaternary organization similar to those of RecT/Redβ and ERF [ 16 26 ] . However, RAD52-like proteins showed no detectable sequence similarity with either the ERF or the RecT/Redβ-like proteins.
The sporadic distribution of this family among phylogenetically distant bacteria, along with its presence in several prophages, suggests that, like the RecT/Redβ and ERF superfamilies, at least the bacterial RAD52-proteins might be of predominantly phage origin.
However, the average size of the core domains, the patterns of conserved residues, and the predicted secondary structures of the RecT/Redβ and ERF domains show no correspondence to each other, implying that there is no direct evolutionary link between these protein groups.
Like ethylene, JA rapidly induces ERF1 expression, and treatment with both hormones synergistically activates ERF1 . Induction of ERF1 by both hormones alone or in combination is dependent upon both signaling pathways, and constitutive overexpression of ERF1 rescues the defense-response defects of both ethylene- and JA-insensitive mutants.
The similarity between these two systems is further extended by the observation that the RecT/E system can complement mutations in the λ exo/Redβ system [ 10 12 ] . In eukaryotes, RAD52 protein has been shown to exhibit properties similar to those of RecT and Redβ proteins: it binds ssDNA and promotes strand exchange via the pairing of complementary single strands [ 6 13 ] . In vitro studies on quaternary structures have shown that the single strand annealing proteins (SSAPs), RecT, Redβ, ERF and RAD52, form similar helical super-structures [ 14 15 16 17 ] . This has led to the proposal that RecT, Redβ, ERF and the eukaryotic RAD52 function in an analogous fashion, and even are "structural homologs" [ 14 ] .
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