Words similar to erbb

Example sentences for: erbb

How can you use “erbb” in a sentence? Here are some example sentences to help you improve your vocabulary:

The molecular mechanisms leading to breast malignancies are unclear, but many genetic abnormalities and epigenetic factors have been implicated, including changes affecting known tumor suppressor genes ( p53 , BRCA1, BRCA2 , PTEN/MMAC1/TEP1) and proto-oncogenes (neu/ErbB2/HER2 , ErbB1/EGFR , PRAD-1/cyclin D1 , Mdm2 , and c-myc) [reviewed in ref.
Genes of the ERBB family encode receptor tyrosine kinases that mediate cellular responses to growth signals.
Some well characterized, physiologically important EPKs, such as ErbB3 [ 36], seem to have lost their enzymatic activity altogether and are thought to function solely as scaffolding proteins.
Somatic mutations in the tyrosine kinase domains of two ERBB genes, epidermal growth factor receptor (EGFR) and HER2, have been found in a proportion of lung adenocarcinomas [1,2,3,4].
ERBB signaling pathways include downstream GTPases encoded by RAS genes.