Words similar to epileptogenic

Example sentences for: epileptogenic

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It has been shown that these malformations, resembling human microgyria, are associated with widespread disturbances in neuronal organization [ 4 5 ] . For example, brain slices containing microgyric cortex show increased epileptogenic activity [ 6 7 8 9 ] . Microgyric anomalies are also associated with connectional alterations [ 10 11 12 ] , affecting both thalamic and cortico-cortical connectivity.
reported that under epileptogenic condition (free Mg 2+in ACSF), γ band oscillations arise from GABAergic depolarizations and that this activity may lead to the generation of ictal discharges [ 18 ] . It has been reported that prolonged periods of γ oscillations are associated with temporal lobe seizures in in vivo rats [ 41 ] . Furthermore, human EEG studies with subdural recording electodes showed that a γ band oscillation could be recorded at the start of typical seizure activity [ 42 ] . In this respect, the hyperthermic γ oscillations may also play a critical role in generation of neuronal epileptiform activity.
However, this simple balance model has been challenged by findings that GABAergic transmission remains effective in some epilepsy models, in epileptogenic human tissue [ 34 35 36 37 38 39 40 ] , and by current findings of the excitatory effects of GABA [ 18 22 23 ] . Therefore, the GABA excitatory effects may work as a possible ictogenic mechanism under some special condition such as tetanic stimulation.