Words similar to epigenetic

Example sentences for: epigenetic

How can you use “epigenetic” in a sentence? Here are some example sentences to help you improve your vocabulary:

Distinct patterns of promoter methylation between SCC and AC, however, suggest that epigenetic pathways of tumor suppression may be different in these histologic subtypes.
Epigenetic imprints affecting the expression of nuclear genes differ in the efficiency with which they are relayed onto homologous sequences.
Microsatellite instability (MSI) is hallmark of mismatch repair-deficient cancers, which has been observed in all cancers arising from Hereditary Non-polyposis Colorectal Cancer (HNPCC) syndrome, some sporadic colorectal and other cancers [ 38 ] . MSI is generally associated with germ-line mutations in one of two MMR genes, hMLH1 and hMSH2 . Epigenetic inactivation of promoter hypermethylation of APC and HIC1 also results in MSI phenotype in sporadic colorectal cancers [ 39 40 ] . Accumulating evidence supports the view that promoter methylation of mismatch repair genes may be related to MSI phenotype [ 41 42 ] . A number of previous studies have shown the existence of MSI phenotype in CC [ 43 44 ] . In the present study, we found that MSI-H occurs at an increased frequency in tumors with HIC1 and APC promoter hypermethylation.
The first comparison relates to the speed of epigenetic change.
In contrast, a trans-methylated singlet PAI2 gene did not trans-methylate a naive allelic PAI2 gene within three generations [ 12 ] . Additional experimentation may eventually provide an answer to the question of what controls the efficiency of such epigenetic interactions.