Words similar to enzyme-substrate

Example sentences for: enzyme-substrate

How can you use “enzyme-substrate” in a sentence? Here are some example sentences to help you improve your vocabulary:

These methods can contribute significantly to the understanding of structural and energetic basis of enzyme-substrate interactions [ 7 8 9 ] .
On the other hand, if the major function of Hnt2 depends on formation of an enzyme-substrate complex [ 16 ] , then synthetic lethal interactions ought to be sought in heat shocked ADE2 HNT2-His109Ala strains.
This bias normally influences both the orientation and conformation of the ligand in the active site, which usually represents a local minimum conformation [ 14 ] . More importantly, the lock and key concepts used to evaluate enzyme-substrate binding, in reality, refer to flexible locks and keys that are both in constant dynamic (thermal) motion [ 15 ] . For example, an analysis of conformational changes upon complex formation for a representative set of 39 pairs of ligand-free and ligand-bound structures showed that 50% of these proteins undergo substantial main-chain and side chain conformational changes when the ligand is bound [ 15 ] .
Since most current docking programs treat the receptor and/or ligand as rigid objects, this represents an important cause of failure to predict the correct binding enzyme-substrate energies [ 18 ] . We address this problem by performing Molecular Dynamic (MD) simulations on HIV-1 protease-inhibitor complexed and using the resulting structures to calculate the binding energies by AutoDock, a ligand flexible docking program.