Words similar to endometrial
Example sentences for: endometrial
How can you use “endometrial” in a sentence? Here are some example sentences to help you improve your vocabulary:
M6P/IGF2R loss of heterozygosity occurs frequently in human breast, liver and lung cancer [ 6 20 21 22 ] , and the remaining allele of 30 to 50% of these tumors contains an intragenic loss-of-function point mutation in the ligand binding domains [ 35 ] . The M6P/IGF2R is also commonly mutated in gastrointestinal and endometrial malignancies because its coding sequence contains a poly-G region that is a mutational target in tumors with mismatch repair deficiencies and microsatellite instability [ 23 24 ] . Functional studies show that the introduction of an exogenous wild-type M6P/IGF2R into human colorectal cancer cells with a single inactivated allele significantly decreases growth rate and enhances apoptosis [ 26 ] . Conversely, loss of M6P/IGF2R expression promotes cancer cell growth by increasing intracellular signaling from both the insulin-like growth factor I receptor and the insulin receptors [ 36 ] .
Increase in IL-1β gene expression was specific to the conceptus as endometrial expression was unchanged between cyclic and pregnant gilts.
And for some cancers there was a familial association with other cancers, for example, relatives of individuals with stomach, colon, rectal, or endometrial cancer were more likely to have any of these cancers.
Based on its antiprogesterone activity, RU486 has been evaluated as a useful anticancer agent in organs sensitive to this hormone [ 4 ] . Although evidence was not conclusive in these studies, RU486 demonstrated a benefit to humans suffering from meningioma, breast cancer and uterine leiomyomata [ 4 ] . Several in vitro studies also demonstrated that RU486 induced antiproliferative effects against murine mammary tumors [ 5 ] as well as cultured human endometrial stromal and epithelial cells [ 6 7 ] .
In the light of strong associations previously noted between estrogens and corpus uteri cancer, BMD should predict the occurrence of endometrial cancer [ 4 ] , though this has not yet been directly assessed.
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