Example sentences for: end-point

How can you use “end-point” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These data suggest that the 28-day all-cause mortality rates reported for drotrecogin alfa (activated) represent a composite end-point of less sepsis-induced death, potentially less thrombotic-related deaths, as well as any fatal complications associated with the use of drotrecogin alfa (activated).

  • According to these criteria a protocol has been optimized for routine use (Table 1) that allows detection of the 1-2 copies of HPV 16 DNA integrated into the genome of SiHa cells utilizing a chromogenic end-point.

  • In the present study we used a carcinogen-induced rat mammary carcinogenesis model to test the hypothesis that chemoprevention by tamoxifen and retinoids is associated with local upregulation of TGF-βs in the mammary gland, and that TGF-βs might therefore be useful as potential surrogate end-point biomarkers of chemopreventive efficacy in clinical trials.

  • Because these values represent the starting and end-point IL-1Ra concentrations, the effective tIL-1Ra dose should lie somewhere between and is represented by the shaded area between the two curves.

  • This suggested that the chemopreventive action of these agents against breast cancer could be mediated in part through enhancing the tumor suppressor activity of the endogenous TGF-β system, and thus that changes in TGF-β expression might serve as useful surrogate end-point biomarkers of chemopreventive efficacy.


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