Words similar to eik

Example sentences for: eik

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Triggering of the UPR also results in the suppression of global protein synthesis, as PERK is activated and phosphorylates EIK2α, which can only interact with the appropriate ribosomal binding sites in an unphosphorylated state [ 11 12 ] . While the upregulated transcription of PERK is not required for its activation, it's over expression can lead to the enhanced phosphorylation (and therefore inactivity) of EIK2α [ 16 ] . Therefore, its up-regulation by mefloquine supports the hypothesis that the drug triggers an UPR.