Example sentences for: egf-like

How can you use “egf-like” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It is well established that EGF-like modules are important structural features found in many extracellular proteins and that these modules enable numerous protein :protein interactions; the binding of EGF-like modules in laminin to nidogen [ 19 ] and the interaction of EGF-like modules within fibrillin monomers [ 20 21 ] . Calcium may be required for some of these protein interactions.

  • The amino acid sequence of the heparin-binding region of HB-EGF ( 21KRKKKGKGLGKKRDPCLRKYK 41) [ 2 ] has been shown to have a strong affinity for heparin and may influence the interaction of this growth factor with cell-surface negatively charged heparan sulfate proteoglycans [ 22 ] . It remains to be seen whether specific/all of the EGF-like modules are required and whether calcium is needed for the interaction of HB-EGF with LTBP-3.

  • The co-expression that we observed in our analysis for the EGF-like domains and immunoglobin superfamily suggested that they may cooperate with each other in the cell adhesion process.

  • In constrast, the construct, pGAD424/Fib-1C EGF#1-5, that contained calcium-binding type II EGF-like modules #1-5 fused to the GAL4 activation domain (see Fig.

  • Deletion of the EGF-like domains encoded by exons 60-62 in the C-terminal domain of fibrillin-1 results in a much less severe phenotype than deletion of three EGF-like domains in the second longest stretch of EGF-like domains (between exons 43-49).


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