Words similar to egf-like
Example sentences for: egf-like
How can you use “egf-like” in a sentence? Here are some example sentences to help you improve your vocabulary:
Nidogen is a basement membrane protein composed of three globular domains G1-G3 and two linking sequences; domain G1 is joined to domain G2 through a flexible link and domain G2 is connected to domain G3 by a rod-like element consisting of EGF-like modules [ 47 ] . Nidogen1 is an important structural component of tertiary complexes with other such extracellular components as laminins, collagen IV, perlecan, and fibulins [ 48 ] . Fibulin-1C binds to nidogen1 through domain G2 of nidogen [ 48 ] . The nidogen binding site of fibulin-1C includes the type II EGF-like modules 6-9 and the carboxyl-terminal domain [ 42 ] .
Fibulin-1 has been reported two exhibit calcium-dependent self-association [ 40 44 ] . The two self-association sites map to type II EGF-like modules 5 and 6 and to a cryptic site in the amino-terminal region of fibulin-1 [ 40 44 ] .
The calcium-binding type II EGF-like modules #1-8 of monkey LTBP-3 (Fig.
Each has a signal sequence (55 amino acids and 49, respectively), a second domain containing an EGF-like repeat, a proline/glycine rich region, a fibrillin motif [ 17 ] , an EGF calcium-binding repeat, and a TGF-β repeat (390 and 389 amino acids, respectively), a third domain containing a proline/glycine rich region (113 and 111 amino acids, respectively), a fourth domain containing numerous calcium-binding type II EGF-like modules (D/N)(I/V)(D/N)(E/D)C 1 (678 and 677 amino acids, respectively) and a fifth carboxyl-terminal domain (5 and 21 amino acids, respectively) (human LTBP-3 information was obtained from the GenBank database accession no.
Deletion of the EGF-like domains encoded by exons 60-62 in the C-terminal domain of fibrillin-1 results in a much less severe phenotype than deletion of three EGF-like domains in the second longest stretch of EGF-like domains (between exons 43-49).
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