Words similar to egf-like
Example sentences for: egf-like
How can you use “egf-like” in a sentence? Here are some example sentences to help you improve your vocabulary:
It is interesting that the combination of colony hybridization and yeast two-hybrid screens used in this study to identify proteins that interact with the extracellular domain of proHB-EGF yielded independent GAL4-LTBP-3 fusion proteins that all contained these calcium-binding type II EGF-like domains (Fig.
These negatively-charged EGF-like modules of LTBP-3 may interact efficiently with the positively-charged heparin-binding domain of both the membrane-bound and soluble forms of HB-EGF.
At the time of writing, there have not been any reported interactions of these EGF-like modules in LTBP-3 proteins with specific proteins.
Aggrecan and versican are aggregating proteoglycans that are key constituents found in the extracellular matrix [ 41 ] . Both proteoglycans contain amino-terminal hyaluronic acid-binding regions, central core glycosaminoglycan attachment domains, and carboxyl-terminal domains containing EGF-like modules (one in aggrecan and two in versican), C-type lectin like modules and complement regulatory protein-like modules [ 49 50 ] . Fibulin-1 exhibits calcium-dependent binding to the carboxyl-terminal domain of aggrecan and versican [ 41 ] . The binding site of aggrecan to fibulin-1 maps to the type II EGF-like modules 8-9 and the carboxyl-terminal domain of fibulin-1 [ 41 ] . The binding site of versican to fibulin-1 maps to the type II EGF-like modules 2-8 of fibulin-1 [ 41 ] .
Deletion of the EGF-like domains encoded by exons 60-62 in the C-terminal domain of fibrillin-1 results in a much less severe phenotype than deletion of three EGF-like domains in the second longest stretch of EGF-like domains (between exons 43-49).
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