Words similar to ectodomain
Example sentences for: ectodomain
How can you use “ectodomain” in a sentence? Here are some example sentences to help you improve your vocabulary:
The outer surface of the coiled-coil contains grooves into which three heptad repeat regions from the C-terminal part of the gp41 ectodomain pack, resulting in a stable six-helix bundle [ 42 45 46 47 48 49 50 51 52 53 54 ] . The six-helix bundle structure can be detected by specific antibodies [ 14 20 43 55 ] .
In our paper [2], we present evidence that the isoprenoid pathway contributes to statin-activated shedding of the APP ectodomain in cultured cells.
Despite this, however, the association of statins and cholesterol levels with activated α-secretase-mediated shedding of the APP ectodomain was unexpected and not readily explicable by existing knowledge regarding regulation of α-secretase activity.
More specifically, the data indicate that ROCK1 activation blocks the effects of statins on APP ectodomain shedding, while ROCK1 blockade alone can mimic the effect of statins on APP shedding.
However, the molecular mechanisms by which statins modulate ectodomain shedding remain to be elucidated [17,18].