Example sentences for: ectodomain

How can you use “ectodomain” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Ultimately, the integral cell-surface metalloproteinases ADAM-10 and ADAM-17/TACE were found to underlie α-secretase-type ectodomain shedding [3,46].

  • Why is APP a substrate for ectodomain shedding?

  • The pathway leading to AICD must be initiated by ectodomain shedding: holoAPP cannot directly give rise to AICD.

  • The identification of the regulatory components of the ectodomain shedding machinery have been long-sought in other studies employing phorbol esters to stimulate shedding of sAPP α or TGFα [4,35,36,37].

  • α-Secretase-type ectodomain shedding divides the Aβ domain of APP, thereby generating α-secretase-cleaved soluble APP ectodomain (sAPP α ) [4].


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