Words similar to ebp-

Example sentences for: ebp-

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Induction of the constitutively active 4EBP-1 leads to cell cycle arrest which correlates with loss of cyclin D1 expression and increased levels of the cyclin dependent kinase inhibitor p27 Kip1.
In the present study an MCF7 breast cancer cell line was developed which can be induced to express a mutant form of 4EBP-1 in which five amino acids that are targets for phosphorylation have been changed to alanines [ 24 ] . Since the protein cannot be inactivated by phosphorylation it constitutively binds to and inhibits eIF4E.
In contrast to cyclin D1, p27 Kip1levels increase when 4EBP-1-5A is expressed.
MCF7-4EBP-1-5A cells were cultured in the presence or absence of pon A (10 mM) for 48 hours.
Anti-PHAS1 (4EBP-1) polyclonal antibody was purchased from Zymed.