Words similar to ebp-
Example sentences for: ebp-
How can you use “ebp-” in a sentence? Here are some example sentences to help you improve your vocabulary:
To test the effect of 4EBP-1 on the proliferation of human breast cancer cells, an expression vector encoding the constitutively active 4EBP-1 mutant (4EBP-1-5A) was stably transfected into MCF7 cells.
A single stably transfected cell line designated MCF7-4EBP-1-5A was used in the experiments described.
This increase is similar to that observed for endogenous p27 Kip1in cells induced to express 4EBP-1-5A.
This property is shared by the highly homologous mouse p27 Kip15'-UTR [ 28 ] . Coexpression of 4EBP-1-5A with the bicistronic construct containing the p27 Kip15'-UTR leads to an approximately two-fold increase in cap-independent expression.
These results indicate that expression of constitutively active 4EBP-1 leads to cell cycle arrest of MCF7 cells.