Words similar to ebp

Example sentences for: ebp

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A portion of the cellular eIF4E is imported into the nucleus through a mechanism that requires the protein 4E-T [ 31 ] . In the nucleus eIF4E is localized to specific nuclear bodies and associates with promyelocytic leukemia protein (PML, [ 32 ] ). Nuclear eIF4E appears to be involved in export of cyclin D1 mRNA to the cytosol [ 25 ] . Both 4E-T and PML interact with the same domain of eIF4E that binds 4EBP [ 32 ] . Thus expression of constitutively active 4EBP may block nuclear functions of eIF4E, one consequence being a reduction in cyclin D1 mRNA that can be translated in the cytoplasm.
The observed decline in cyclin D1 is expected since constitutively active 4EBP should reverse cyclin D1 expression mediated by eIF4E overexpression.
Recent studies have demonstrated upregulation of C/EBP in lung injury induced by LPS in vivo [ 52 53 ] . Our findings are consistent with this report and suggest that this transcription factor may be a marker of tissue injury.
Thus, whereas CREB activity peaked 0.5 hours after endotoxin administration, C/EBP binding activity was maximal at 12 hours.
The No C/EBP controls also indicated the extent to which green fluorescent, C/EBPα-expressing cells were distinguished from non-expressing cells by flow cytometry.