Words similar to eae
Example sentences for: eae
How can you use “eae” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus, some of us recently showed that administration of two self peptides that can induce EAE, myelin proteolipid protein peptide 139 to 151 (PLP139-151) or myelin oligodendrocyte glycoprotein peptide 35-55 (MOG35-55), can result in severe anaphylactic reactions [ 14 ] . This result clearly indicated that severe allergic reactions to self peptides can occur in mice that have been induced to express pathology (i.e.
Thus, in both the EAE model [ 14 ] and the NOD T1DM model (this study, and that of Liu et al ., [ 15 ] ) some form of artificial "immunization" with a self peptide preparation appears to be required for the development of anaphylactic reactivity to "self".
, EAE, T1DM in NOD mice) was anaphylaxis associated with histological evidence of substantial mast cell degranulation [ 14 ] (data not shown).
There were both similarities and differences between our findings in the NOD mouse model of T1DM and those in the EAE model [ 14 ] . Expression of EAE requires specific immunization with self peptides (e.g.
For example, this agent is a potent inhibitor of microglia, the macrophage-like cells in the central nervous system [ 47 48 49 ] and shown to be effective in reducing the symptoms of experimental autoimmune encephalomyelitis (EAE), an animal model for the human disease multiple sclerosis [ 50 ] . Together, these results suggest that this agent may be useful in preventing ocular diseases that result from oxidative stress or inflammation.
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