Example sentences for: eae

How can you use “eae” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • [ 14 ] is whether the influence of thymic expression of the self peptide on the propensity to develop anaphylactic reactivity differs in the EAE and NOD T1DM models.

  • For example, this agent is a potent inhibitor of microglia, the macrophage-like cells in the central nervous system [ 47 48 49 ] and shown to be effective in reducing the symptoms of experimental autoimmune encephalomyelitis (EAE), an animal model for the human disease multiple sclerosis [ 50 ] . Together, these results suggest that this agent may be useful in preventing ocular diseases that result from oxidative stress or inflammation.

  • There were both similarities and differences between our findings in the NOD mouse model of T1DM and those in the EAE model [ 14 ] . Expression of EAE requires specific immunization with self peptides (e.g.

  • Thus, in both the EAE model [ 14 ] and the NOD T1DM model (this study, and that of Liu et al ., [ 15 ] ) some form of artificial "immunization" with a self peptide preparation appears to be required for the development of anaphylactic reactivity to "self".

  • Whatever the underlying reason(s) for the development of anaphylactic reactivity to these self peptide preparations, in both the EAE and the NOD T1DM models, anaphylactic reactions occurred in mice that had developed strong IgG1 responses to the relevant self peptides, with only modest changes in total IgE levels.


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