Words similar to dystrophin

Example sentences for: dystrophin

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Additional file B: Details regarding procedure and cost of DHPLC screening, observations regarding the dystrophin gene, and statistics about DMD carrier females.
LIF and CNTF stimulate muscle regeneration in vivo [ 62 63 ] , as do other growth factors; such as insulin-like growth factor [ 64 65 ] . The power of LIF to regenerate muscle is seen in dystrophin null mdx mice, where exogenous LIF regenerates atrophied diaphragm muscle [ 66 ] . LIF induced signaling appears to be essential in muscle development as seen by muscle atrophy in the absence of LIFR on E18.
Dystrophin and its associated proteins are thought to be involved in the anchoring of the muscle cell membrane to the extracellular matrix [ 1], and the absence of many of these proteins can lead to the phenotype of muscular dystrophy [ 2].
Although none of the patients had a family history of DMD, all were determined to be highly likely to have dystrophin gene mutations, as opposed to other genetic causes of muscular dystrophy (see Table 1).
A second subcomplex, known as the dystroglycan complex [ 6], interacts directly with dystrophin in the cytoplasm and laminin in the extracellular matrix, thus providing a structural link between the inside and the outside of the cell.