Example sentences for: dystrophin

How can you use “dystrophin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Initially the primers were used to prepare amplicons of dystrophin exons for direct sequencing.

  • Patients with autosomal dominant limb girdle muscular dystrophy type 1C, caused by mutations in caveolin-3 [ 19, 20], or autosomal recessive LGMD2B, caused by mutations in dysferlin, show normal dystrophin and sarcoglycan-sarcospan complex staining patterns [ 21].

  • Sarcospan immunoreactivity is altered in both Duchenne Muscular Dystrophy and the sarcoglycanopathies (LGMD2C-F) and appears to be very sensitive to disturbances in the dystrophin associated protein complex [ 16].

  • Although none of the patients had a family history of DMD, all were determined to be highly likely to have dystrophin gene mutations, as opposed to other genetic causes of muscular dystrophy (see Table 1).

  • The DMD gene spans 2.4 million base pairs of genomic DNA on the X chromosome and its 14 kb transcript encodes a full-length protein (dystrophin) of 427 kiloDaltons.


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