Words similar to duplication
Example sentences for: duplication
How can you use “duplication” in a sentence? Here are some example sentences to help you improve your vocabulary:
On the basis of the findings of Pujana et al ., the GLP/LCR15 duplicon is present at multiple regions of human genomic instability [ 21 ] . In addition, the GLP/LCR15 duplicon was shown by Gilles et al . to be polymorphic in the human population - showing that these sequences have considerable intraspecific plasticity [ 18 ] . The GLP/LCR15 duplication family has expanded over the last 20 million years of primate evolution, before the divergence of the great ape lineages, resulting in a multitude of copies (estimated at 27) present at multiple sites along chromosome 15, providing the conditions required for rearrangements driven by nonallelic homologous recombination (NAHR) [ 18 19 21 27 ] . We have begun an investigation of the organization of this region within the chimpanzee lineage.
However, genome duplication presents significant problems for the faithful transmission of a genome from one generation to the next, and is consequently a rare event, at least in Metazoa.
Gene duplication may be a temporary mechanism to increase protein or RNA dosage, as in the case of rRNA genes in amphibian oocytes and ciliate macronuclei, the chorion genes in some dipterans, actin genes in chicken as well as drug transporters in somatic tissues (see [ 34, 37] for reviews).
Area of Inquiry--Does the configuration of programs within the state maximize the potential for effective and efficient administration and minimize the potential for duplication of capacities, services, systems and/or administration?
As discussed above, data suggest that duplication of genes encoding the TOX-like HMG-box occurred prior to mammalian radiation.
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