Words similar to dslet-mediated
Example sentences for: dslet-mediated
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However, neither of these proteins has been reported to act as a surrogate scaffold during ERK activation by non-opioid GPCRs [ 27 ] . In the present report, DSLET-mediated ERK phosphorylation was unaltered by the presence of the IR or PDGFR antagonists, HNMPA-(AM) 3 and tyrosphostin 9, respectively.
DSLET-mediated ERK activation was significantly inhibited by the Src kinase inhibitor, PP1 (10 μM) (Figure 3).
However, DSLET-mediated ERK activation was unaltered in identically pretreated cultures.
While the EGFR does not appear to be phosphorylated during DSLET-mediated ERK activation, it is possible that the EGFR is somehow involved in this response when it is present.
Furthermore, the EGFR antagonist, AG1478, had no effect on DSLET-mediated ERK activation, which eliminated the possibility that these antagonists produced non-specific, inhibitory effects (Figure 7).