Words similar to dslet-mediated
Example sentences for: dslet-mediated
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Conversely, DSLET-mediated ERK phosphorylation is actually greater in chronically-treated EGF cultures to that observed in cells not previously exposed to high EGF concentrations.
In C6 glioma cells that express the mouse δ-OR, DSLET produced a concentration-dependent increase in the appearance of phospho-ERK 1 and 2. DSLET-mediated ERK activation in C6-δ-OR cells was completely inhibited by either pre-treatment with PTX or naltrindole (data not shown).
EGFR down-regulation does not affect DSLET-mediated ERK activation in HEK-293 cells
In a similar experiment, a 24-hour exposure to DSLET (10 μM) induced significant δ-OR down-regulation and an almost complete loss of DSLET-mediated ERK phosphorylation.
DSLET-mediated ERK activation was significantly inhibited by the Src kinase inhibitor, PP1 (10 μM) (Figure 3).