Words similar to dslet
Example sentences for: dslet
How can you use “dslet” in a sentence? Here are some example sentences to help you improve your vocabulary:
WT-δ-OR-expressing HEK-293 cells were exposed to increasing concentrations of either DSLET (1-1000 nM) or EGF (0.
In conclusion, we report that the δ-OR agonist, DSLET, induces significant ERK activation in the absence of any increase in phosphorylation of the co-expressed EGFR in HEK-293 cells.
As stated earlier, either DSLET or EGF increased the appearance of phosphorylated ERK in a time and concentration dependent manner.
Despite the lack of direct evidence that DSLET induces the transactivation of co-expressed RTKs, it is possible that the EGFR, in some way, contributes to ERK activation by opioids.
These results suggest that DSLET utilizes a G i -coupled δ-OR to stimulate ERK 1 and 2. We then took advantage of the HEK-293 cell line's endogenous expression of the EGFR to examine this receptor's ability to activate ERKs.