Words similar to dslet
Example sentences for: dslet
How can you use “dslet” in a sentence? Here are some example sentences to help you improve your vocabulary:
The opioid agonist, [D-Ser-Leu-enkephalin-Thr (DSLET), was received from the National Institute of Drug Abuse (NIDA, Baltimore, MD) and the antagonist, naltrindole, was purchased from Research Biochemicals, Inc., (Natick, MA).
These results suggest that DSLET utilizes a G i -coupled δ-OR to stimulate ERK 1 and 2. We then took advantage of the HEK-293 cell line's endogenous expression of the EGFR to examine this receptor's ability to activate ERKs.
In conclusion, we report that the δ-OR agonist, DSLET, induces significant ERK activation in the absence of any increase in phosphorylation of the co-expressed EGFR in HEK-293 cells.
In a similar experiment, a 24-hour exposure to DSLET (10 μM) induced significant δ-OR down-regulation and an almost complete loss of DSLET-mediated ERK phosphorylation.
Similar to DSLET, EGF (5 ng/ml) produces a robust activation of ERKs in δ-OR-expressing HEK-293 cells after a 5 minute treatment (Figure 2a).
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