Example sentences for: double-strand

How can you use “double-strand” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The complex intermediate forms accumulating in these mutants may be trapped in the agarose gel (see [ 24 25 ] ). An alternative interpretation could be that these enzymes may be involved in generation of double-strand breaks as hypothesized by Seigneur et al.

  • V(D)J recombination proceeds by the introduction of double-strand DNA breaks (reviewed in [ 41]).

  • Processing of pri-miRNA into the pre-miRNA stem-loop occurs in the nucleus, while subsequent processing of pre-miRNA into 21-22 mers is a cytoplasmic event mediated by the RNAse III enzyme Dicer [ 17 18 19 20 ] ; Dicer is also responsible for cleavage of long perfectly double-stranded RNA into 21-22 nucleotide fragments during RNA interference (RNAi) [ 2 21 ] . These latter molecules, known as silencing RNA (siRNA), bind to and trigger the degradation of perfectly homologous mRNA molecules via RISC, a double-strand RNA-induced silencing complex containing nuclease activity [ 22 23 ] .

  • Recall that double-strand breaks are the sites where recombination is initiated during meiosis, and that this is true regardless of the presence of hotspots for both phenomena.

  • The handedness of the initial double-strand helix is preserved throughout fiber morphogenesis suggesting that each cycle of supercoiling is a result of negative twist rather than simple over tightening of the previous helical form into a positive supercoil [ 5 ] .


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