Words similar to double-strand
Example sentences for: double-strand
How can you use “double-strand” in a sentence? Here are some example sentences to help you improve your vocabulary:
There follows a rapid winding up of the filament into a double-strand helix by a process of supercoiling that is triggered by the impediment of the twisting motions that accompany cell growth [ 2 ] . The cells in double-strand helical structures also twist as they grow.
double-strand cutting activity, and thereby explaining coupled action between chromatid cutting and telomere addition (see below).
Game and his colleagues have developed a sensitive means of detecting chromosomal ds breakage using a circular chromosome [ 3 ] . Under most conditions of pulsed-field gel electrophoresis, a circular yeast chromosome and circular bacterial chromosomes will not enter the gel, very likely because they are trapped by the branches of the network of agarose [ 3 13 14 ] . One double-strand break transforms this circular form into a linear form, which can now move slowly in the gel [ 3 ] . We used this procedure to detect double-strand breakage of a circular bacterial chromosome occurring spontaneously or after loss of a restriction-modification gene complex [ 15 16 ] . We found increased chromosome breakage in recBC -null and recC1002 mutants of E. coli under both conditions [ 1 ] . Michel and her colleagues used pulsed-field gel electrophoresis to detect degraded chromosomal DNAs arising spontaneously in recBC mutants and arising during replication fork arrest [ 2 ] . RuvABC proteins, which catalyze migration and cleavage of Holliday junctions, are responsible for the occurrence of the degraded DNAs following replication fork arrests [ 17 ] .
The handedness of the initial double-strand helix is preserved throughout fiber morphogenesis suggesting that each cycle of supercoiling is a result of negative twist rather than simple over tightening of the previous helical form into a positive supercoil [ 5 ] .
V(D)J recombination proceeds by the introduction of double-strand DNA breaks (reviewed in [ 41]).
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