Words similar to dosage-sensitive

Example sentences for: dosage-sensitive

How can you use “dosage-sensitive” in a sentence? Here are some example sentences to help you improve your vocabulary:

Equally important, other studies have shown that loss-of-function and naturally occurring mutations in BMP ligands and receptors are associated with dysregulation of folliculogenesis and ovulation [ 14 15 16 17 18 19 ] . Of particular interest is the finding that ewes having a mutation in the bmp15 gene in both alleles are infertile whereas the heterozygotes are superfertile [ 16 ] . Thus, the bmp15 gene can control ovulation quota through a dosage-sensitive mechanism.
The fact that we recovered recessive, semi-dominant, and dominant mutants in additional tab genes suggests that there are likely to be multiple dosage-sensitive positive and negative regulatory controls that act downstream of or parallel to CDC15.