Words similar to dosage
Example sentences for: dosage
How can you use “dosage” in a sentence? Here are some example sentences to help you improve your vocabulary:
Not surprisingly, a recent report that assessed the angiogenic response in a murine corneal pocket model to a fixed dosage of FGF-2 in various strains of mice suggested that genetic backgrounds may influence angiogenic response [ 30].
However, only one rRNA operon is present in each subspecies and this is also true for the fast growers Mycobacterium abscessus and Mycobacterium chelonae [ 32 ] . These fast growing mycobacteria have multiple promoters that increase the transcriptional rate of the rRNA operon to overcome gene dosage limitations [ 32 ] . The rRNA operon promoter structures have not been mapped by primer extension for either M. paratuberculosis or M. avium , but if M. avium had multiple functional rRNA operon promoters, that may account for the growth rate differences.
The clinical pharmacist received approval from the hospital credentials committee, the pharmacy & therapeutics committee, and the director of dialysis to prescribe and make dosage adjustments and order laboratory tests as per a lipid management guideline.
Furthermore, there is evidence from the analysis of the yeast genome that duplicated genes tend to be from those sets of functions that are more highly expressed [ 62], supporting a general role for selection on protein dosage in duplicated genes.
The generation of Hoxc-8 transgenic mice and the characterization of their phenotype have been published [ 1 ] . Briefly, Hoxc-8 expressing mice are generated in a binary transgenic mouse system [ 44 ] by crossing a transactivator strain (harboring a transgene in which expression of the transcriptional transactivator VP16 is under control of the Hoxc-8 promoter; [ 45 ] ) to a transresponder strain (that carries as a transgene the Hoxc-8 cDNA linked to the ICP4 immediate early gene promoter, which is silent in mice in the absence of VP16; [ 45 46 ] ). Upon combination of both transgenes, the Hoxc-8 transresponder transgene is activated, and Hoxc-8 becomes overexpressed [ 23 ] . This system also allows the generation of transgenic mice with increased gene dosage by superimposition of transgene loci to homozygosity [ 23 44 ] . For the studies reported here, we used the T239 transactivator and the IE-c8-254 transresponder strains.
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