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Example sentences for: dolad

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However, the notion that similarities exist between the HIV +and the aged states with respect to the CD8 +CD28 -T cell has been presented previously [ 55 ] . It has also been proposed that the CD8 +CD28 -T cell in the HIV +state is derived from the CD8 +CD28 +cells by clonal expansion induced by massive antigenic stimulus (HIV proteins) since both showed the same epitope repertoire [ 26 ] . Dolad et al [ 56 ] have shown that the CD8 +CD28 -cell, not the CD8 +CD28 +cell, comprises the major CTL activity in the HIV +state, a finding confirmed by Vingerhoets et al [ 57 ] , who associated cytotoxic T cell activity with the CD8 +CD28 -T cell in HIV-infected subjects.