Example sentences for: discrete

How can you use “discrete” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The MASIA program can parse sequences into discrete blocks of significant conservation.

  • It could then be argued that, given the discrete nature of biological sequences, new scale-independent numerical representations, such as USM, are all but the first step in the identification of more accurate Boolean equivalents of fundamental relevance.

  • This should result in the expression of encoded genes in target cells in an array format, in which each encoded gene should be expressed in a discrete cell spot while maintaining the original location of the viral vector spot in the virus array.

  • On the other hand, microvilli are more permanent discrete cylindrical projections about 0.1 μm in diameter and up to 2 μm in length [ 29] that may serve different purposes, such as in brushborder membranes of the intestinal epithelium or in lymphocytes.

  • Rab proteins comprise a large family of Ras-related GTPases that function in the anterograde and retrograde trafficking of proteins in mammalian cells [ 1 2 3 ] . Different Rab proteins reside in specific subcellular membranes or organelles, where they mediate vesicular transport between discrete donor and acceptor compartments in the endocytic or exocytic pathways [ 4 5 ] . Detailed studies of a few Rab proteins ( e.g .; Rab1, Rab5 and Rab9) have led to a general model wherein Rab proteins are presumed to cycle on and off donor and acceptor membranes in connection with changes in their guanine nucleotide state [ 6 7 8 ] . In the active GTP-bound state, Rab proteins associate with budding transport vesicles [ 9 10 11 ] and appear to participate in the assembly of membrane docking complexes [ 12 13 14 ] . Following vesicle fusion with the acceptor compartment and GTP hydrolysis, the inactive GDP-bound Rab is extracted from the membrane by a carrier protein termed guanine nucleotide dissociation inhibitor (GDI) [ 15 16 17 ] . The GTPase can then re-enter the transport cycle through nucleotide exchange promoted by a specific exchange factor at the donor vesicle membrane [ 18 19 20 ] . In addition to changes in guanine nucleotide state, the posttranslational prenylation of Rab proteins plays an important role in the cycling mechanism.


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