Words similar to dilatation
Example sentences for: dilatation
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The PT1 can be viewed as placenta capable of fulfilling the demands of the growing fetus (occasional villous regeneration and expansion of existing mature villi), without requirement of adaptive dilatation of villous sinusoids.
Table 1shows that abnormal placentae include either advanced placental aging with an excess of villous blood sinusoid dilatation (PT3) or severe villous immaturity without significant dilatation of villous sinusoids (PT4).
During the third trimester, and after 34-36 weeks of pregnancy in particular, the placenta may develop an abnormality, often classified as placental aging [ 19 20 21 22 23 24 ] . These abnormal placentae are characterized by generalized interstitial fibrosis and fibrinoid degeneration of villous stroma, and are associated with cellular apoptosis and congestion of villous sinusoids [ 24 25 26 27 ] . Immunohistochemically, villous abnormality is associated with progressive diminution of Thy-1 differentiation protein in the villous core [ 28 ] . Marked changes in villous structure are particularly associated with advanced maternal age [ 29 30 ] . We have recently reported that, with respect to the Thy-1 expression, compensatory dilatation of villous sinusoids, and placental expression of low molecular weight cyclin E variants, the term placentae can be classified into four placental types (PT1-PT4) [ 30 ] , where PT4 corresponds to the most severe placental abnormality.
When analysing the haemodynamic data, a difficulty can arise in interpreting the pulmonary capillary wedge pressure increase; whether this change is due to an increase in left ventricular preload that follows the increase in venous return, or to a decrease in left ventricular compliance as a result of the leftward shift of the interventricular septum for right ventricular dilatation [ 16, 22].
Carvedilol prevented progressionof LV systolic dysfunction and LV dilatation as previously reportedin other models using β-blockers [ 18 26 ] .
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