Words similar to diet-induced

Example sentences for: diet-induced

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In any case, none of these considerations compromise the basic observation that adrenalectomy failed to reverse diet-induced obesity.
As observed in leptin-deficient ob/ob mice, adrenalectomy in diet-induced obese mice led to a striking increase in hypothalamic POMC mRNA (Fig.
In contrast to other models of obesity, however, diet-induced obesity was not associated with either elevated glucocorticoid levels or reduced hypothalamic POMC mRNA.
4A; p < 0.0001) and as with total heat production adrenalectomy slightly but statistically increased VO 2 in the diet-induced obese mice group (Fig.
Although the mechanisms through which adrenalectomy acts to reverse obesity is not entirely clear, it is plausible that the mechanisms entail enhanced hypothalamic POMC production [ 6 ] . Hypothalamic POMC mRNA is reduced in several forms of obesity [ 18 19 20 ] . Conversely, reversal of obese phenotypes by adrenalectomy is associated with a restoration of hypothalamic POMC mRNA tone in leptin-deficient ob/ob mice [ 6 ] . Furthermore, the melanocortin agonist MTII (which mimics the key anti-obesity product of POMC, alpha-MSH) reduces body weight in diet-induced obesity [ 21 ] . On the other hand, the effect of diet-induced obesity on hypothalamic POMC mRNA is somewhat complex and may depend on the genetic background [ 22 23 ] , and duration of the diet [ 24 25 ] or composition [ 23 ] of the diet.