Words similar to dicistronic
Example sentences for: dicistronic
How can you use “dicistronic” in a sentence? Here are some example sentences to help you improve your vocabulary:
In order to categorize a transcript as dicistronic, we required that each CDS exceed 50 amino acids in length and show some similarity to known proteins.
Among the examples we encountered while annotating the D. melanogaster genome were: the occurrence of distinct transcripts with overlapping UTRs but non-overlapping coding regions, leading us to modify our original definition of 'alternative transcript'; the existence of dicistronic genes, two or more distinct and non-overlapping coding regions contained on a single processed mRNA, requiring support for one to many relationships between transcript and peptides; and trans -splicing, exhibited by the mod ( mdg4 ) gene [ 39], requiring a new data model.
In addition, issues such as determining alternative transcripts, understanding promoter usage, identifying polyadenylation sites, distinguishing genes within the intron of another gene, and recognizing dicistronic genes, are all outstanding problems in the annotation of protein-coding genes.
However, most of the annotated dicistronic pairs are separated by several hundred base pairs, and the separation can be as much as 4.5 kb.
Supplementary tablesof annotated pseudogenes, the distribution of alternatively spliced transcripts, and dicistronic genes, along with the guidelines for re-annotation, are available with the online version of this paper.