Words similar to dicer

Example sentences for: dicer

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The reason(s) for the differential levels of expression is unclear, but it is of interest to note that the mouse Dicer transcript is also prominently expressed in brain and heart tissue, while only lightly expressed in skeletal muscle [ 17 ] . Interestingly, an additional species (~3.
Second, there appears to be measurable selective pressure on the sequence of the non-miRNA arm, above and beyond the necessity to maintain a certain degree of helical structure that would make it a Dicer substrate.
Similar to siRNAs, the natural small RNAs, dubbed microRNAs (miRNAs), arise from Dicer processing of dsRNA precursors and are incorporated into RISC (Denli and Hannon 2003).
The eukaryotic RDRP is part of a large ensemble of functionally linked proteins, which include the Dicer helicase-nuclease, PIWI family proteins, the Hen-2/Corymbosa-like RNA methylase, AlkB-related RNA demethylases, and Lin28-like RNA-binding proteins [ 1 45 46 ] . Since no closely related homologs of any of these proteins are encoded in the genomes of the phages that encode YRH proteins, the latter are unlikely to function in a biological context similar to that of the eukaryotic RDRPs.
The second mammalian RNase III orthologue also exhibits a single C-terminal dsRBM and tandem catalytic domains, but is otherwise structurally distinct from Dicer as it lacks the helicase and PAZ domains (Figure 1) [ 18 19 ] . Preliminary evidence indicates that this RNase III orthologue participates in rRNA maturation.