Words similar to dicer

Example sentences for: dicer

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Second, there appears to be measurable selective pressure on the sequence of the non-miRNA arm, above and beyond the necessity to maintain a certain degree of helical structure that would make it a Dicer substrate.
The eukaryotic RDRP is part of a large ensemble of functionally linked proteins, which include the Dicer helicase-nuclease, PIWI family proteins, the Hen-2/Corymbosa-like RNA methylase, AlkB-related RNA demethylases, and Lin28-like RNA-binding proteins [ 1 45 46 ] . Since no closely related homologs of any of these proteins are encoded in the genomes of the phages that encode YRH proteins, the latter are unlikely to function in a biological context similar to that of the eukaryotic RDRPs.
Sequence database searches and other studies [ 17 ] have revealed only two RNase III orthologues (Dicer and RNase III) in the mouse and human genomes.
The siRNAs are incorporated into a macromolecular complex which carries out degradation of homologous RNA sequences [ 14 ] . Dicer action serves to inhibit viral infection and retroposon movement, and also plays a role in developmental pathways by cleaving precursors to small regulatory RNAs (reviewed in [ 14 15 ] ). The predicted sequence of the mouse Dicer polypeptide exhibits a single dsRBM and tandem catalytic domains.
has four Dicer-like (DCL) proteins, in contrast to mammals and worms, whose genomes encode only one Dicer protein (Schauer et al.