Words similar to dicer
Example sentences for: dicer
How can you use “dicer” in a sentence? Here are some example sentences to help you improve your vocabulary:
The eukaryotic RDRP is part of a large ensemble of functionally linked proteins, which include the Dicer helicase-nuclease, PIWI family proteins, the Hen-2/Corymbosa-like RNA methylase, AlkB-related RNA demethylases, and Lin28-like RNA-binding proteins [ 1 45 46 ] . Since no closely related homologs of any of these proteins are encoded in the genomes of the phages that encode YRH proteins, the latter are unlikely to function in a biological context similar to that of the eukaryotic RDRPs.
Sequence database searches and other studies [ 17 ] have revealed only two RNase III orthologues (Dicer and RNase III) in the mouse and human genomes.
2000); and identified Dicer, the enzyme that chops dsRNA into short RNAs (Bernstein et al.
Second, there appears to be measurable selective pressure on the sequence of the non-miRNA arm, above and beyond the necessity to maintain a certain degree of helical structure that would make it a Dicer substrate.
Processing of pri-miRNA into the pre-miRNA stem-loop occurs in the nucleus, while subsequent processing of pre-miRNA into 21-22 mers is a cytoplasmic event mediated by the RNAse III enzyme Dicer [ 17 18 19 20 ] ; Dicer is also responsible for cleavage of long perfectly double-stranded RNA into 21-22 nucleotide fragments during RNA interference (RNAi) [ 2 21 ] . These latter molecules, known as silencing RNA (siRNA), bind to and trigger the degradation of perfectly homologous mRNA molecules via RISC, a double-strand RNA-induced silencing complex containing nuclease activity [ 22 23 ] .
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