Words similar to diaminopurine
Example sentences for: diaminopurine
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Naturally occurring analogs of purine and pyrimidine bases have been examined extensively for their ability to increase the thermodynamic stability of DNA:DNA and DNA:RNA duplexes [ 11 12 13 14 15 ] . Among these are 2-aminoadenine also known as diaminopurine (DAP), which is found in S-2L cyanophage DNA [ 16 ] , 5-methyl uracil (MeU), and 5-methyl cytidine (MeC).
Modified ribo- and deoxyribonucleoside analogs have been used in a variety of applications [ 12 13 14 ] , but their use has been limited in the field of microarrays [ 23 ] . We demonstrate that 2-aminoadenosine or 2,6-diaminopurine (DAP), an analog of adenosine, significantly increases signal intensity for a wide range of probe sequences, whereas C-5 methylated pyrimidine analogs of cytosine and uridine decreased signal intensities across the entire range of probe sequences on our platform (Figure 2).