Words similar to deubiquitinating
Example sentences for: deubiquitinating
How can you use “deubiquitinating” in a sentence? Here are some example sentences to help you improve your vocabulary:
It has been proposed that long polyubiquitin chains commit a substrate to unfolding and degradation by the proteasome, whereas short chains are poor substrates because they are edited by deubiquitinating enzymes, resulting in premature substrate release (Eytan et al.
In groundbreaking work, an intrinsic “cryptic” deubiquitinating activity that is sensitive to metal chelators has been reported for the proteasome, in addition to “classic” cysteine protease behavior (Verma et al.
At first glance, the delegation of tasks between the proteolytic subunits of the proteasome (situated in the proteolytic core particle) and the auxiliary deubiquitinating enzymes (situated in the regulatory particle) is clear-cut: the latter cleave between ubiquitin domains, while the core proteolytic subunits process the target protein itself (Figure 1).
Overall, this protein certainly has properties consistent with a metallohydrolase and can serve as the prototype for the deubiquitinating enzymes in its class.
Based on sequence homology, deubiquitinating enzymes were traditionally classified into two families: ubiquitin-specific proteases (UBPs or USPs) and ubiquitin carboxy-terminal hydrolases (UCHs).