Example sentences for: detoxification

How can you use “detoxification” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Permeases, transporters, synthetases and various detoxification enzymes, which, in general, tend to amplify as a response to stressful conditions [ 32, 33, 34, 46, 48, 51], also showed a substantial presence among the recently duplicated genes in all species (see Additional data files).

  • Liver is relevant in toxicology as the primary organ of metabolism and detoxification; it is a recurrent target of chronic drug toxicity.

  • The predicted 2OG-Fe(II) dioxygenase activity of AlkB is probably involved in the detoxification of methylated bases in ssDNA, possibly through hydroxylation of the methyl groups, resulting in less toxic base derivatives.

  • Patients were excluded if they had active Centers for Disease Control (CDC) Class C status; could not comply with the study schedule; were in another investigational drug study; were undergoing opiate detoxification; had a malabsorption syndrome or pre-existing condition that interfered with normal gastrointestinal transit; had clinically significant laboratory abnormalities, required radiation therapy or cytotoxic chemotherapy, or had received immunomodulating agents, within 4 weeks pre-study; or had received an HIV-1 immunotherapeutic vaccine within 3 months pre-study.

  • Both severe hepatitis and acute liver failure have been attributed to SSZ [ 25 26 27 28 ] . Patients with SSZ hepatotoxicity demonstrate a prompt recurrence of symptoms upon rechallenge with SSZ or sulfonamide [ 15 29 30 31 ] . Susceptibility to the toxic effects of SSZ and other sulfonamides may be due to the interaction of metabolic pathways regulating N-acetylation and specific detoxification of the metabolites of the drug [ 32 33 ] . However, it remains unclear if genetic differences in drug metabolizing enzyme expression may increase the risk of SSZ toxicity.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast