Words similar to desensitization

Example sentences for: desensitization

How can you use “desensitization” in a sentence? Here are some example sentences to help you improve your vocabulary:

The mechanisms underlying desensitization or down-regulation of the 5-HT 2C receptor are unknown but these reports suggest finely tuned control of 5-HT 2C receptor function and density.
The predicted topological organization consists of six transmembrane domains with a hydrophobic loop between the fifth and sixth domain which lines the ion conducting pore [ 17 ] . VR1 has been expressed heterologously in several cell lines and has intrinsic sensitivity to thermal stimuli and to capsaicin (a pungent extract of the Capsicum pepper family) [ 18 ] . VR1 does not discriminate among monovalent cations [ 19 ] ; however, it exhibits a notable preference for divalent cations with a permeability sequence of Ca 2+> Mg 2+> Na +≈ K +≈ Cs + [ 9 ] . Ca 2+is especially important to VR1 function, as extracellular Ca 2+mediates desensitization [ 20 21 ] , a process which enables a neuron to adapt to specific stimuli by diminishing its overall response to a particular chemical or physical signal.
While wt receptors desensitized rapidly, mutant receptors showed no desensitization during the 8 s perfusion time.
Lack of desensitization could result from either a stabilization of the open state of the channel or a destabilization of the desensitized state.
That lengthy action means that, although nicotine activates the receptors, it then often turns particular receptor subtypes off again, a process called desensitization.