Words similar to desaturase
Example sentences for: desaturase
How can you use “desaturase” in a sentence? Here are some example sentences to help you improve your vocabulary:
In a study of children with protein-energy malnutrition, Decsi and coworkers [ 23 ] used product/substrate ratios of fatty acids in serum phospholipids to speculate that children with protein-energy malnutrition have a reduced level of Δ5-desaturase activity compared to well-nourished children.
Feeding our diets affected various genes containing a PPRE, with roles in triacylglycerol synthesis (mitochondrial glycerol-3-phosphate acyltransferase, Gpam), FA oxidation (carnitine palmitoyl transferase, Cpt1; dienoyl CoA isomerase, Ech1), FA desaturation (stearoyl-coenzyme A desaturase, Scd1 or Δ9 desaturase), gluconeogenesis (cytosolic phosphoenolpyruvate carboxykinase 1, Pck1 or PEPCK; glucose-6-phosphatase, G6pc), cytochrome p450 metabolism (Cyp4a-10 and -14), FA transport (Cd36; FA binding protein, Fabp5), cholesterol metabolism and transport (apolipoprotein A4, Apoa4; apolipoprotein B-100, ApoB-100), and ketone body formation (mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme A synthase 2, Hmgcs2).
This particular desaturase is a regulatory enzyme in the pathway responsible for the biosynthesis of long-chain polyunsaturated fatty acids in both the n-6 and n-3 fatty acid families [ 24 ] . Since children with SCD exhibit some of the characteristics of malnutrition, such as lower weight-for-age and lower lean body mass, the activity of the)5-desaturase in these children may be decreased, resulting in lower proportions of the long-chain polyunsaturated fatty acids in both serum and membrane phospholipids.
The levels of AA and DHA chosen were similar to that previously shown in rats to affect neurotransmitter levels and behavior [ 96 ] ; and were not excessively high, being 2-3 fold higher than that recommended for human babies who have a slower Δ6 desaturase activity than rodents.
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