Example sentences for: desaturase

How can you use “desaturase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In a study of children with protein-energy malnutrition, Decsi and coworkers [ 23 ] used product/substrate ratios of fatty acids in serum phospholipids to speculate that children with protein-energy malnutrition have a reduced level of Δ5-desaturase activity compared to well-nourished children.

  • The levels of AA and DHA chosen were similar to that previously shown in rats to affect neurotransmitter levels and behavior [ 96 ] ; and were not excessively high, being 2-3 fold higher than that recommended for human babies who have a slower Δ6 desaturase activity than rodents.

  • This particular desaturase is a regulatory enzyme in the pathway responsible for the biosynthesis of long-chain polyunsaturated fatty acids in both the n-6 and n-3 fatty acid families [ 24 ] . Since children with SCD exhibit some of the characteristics of malnutrition, such as lower weight-for-age and lower lean body mass, the activity of the)5-desaturase in these children may be decreased, resulting in lower proportions of the long-chain polyunsaturated fatty acids in both serum and membrane phospholipids.

  • Feeding our diets affected various genes containing a PPRE, with roles in triacylglycerol synthesis (mitochondrial glycerol-3-phosphate acyltransferase, Gpam), FA oxidation (carnitine palmitoyl transferase, Cpt1; dienoyl CoA isomerase, Ech1), FA desaturation (stearoyl-coenzyme A desaturase, Scd1 or Δ9 desaturase), gluconeogenesis (cytosolic phosphoenolpyruvate carboxykinase 1, Pck1 or PEPCK; glucose-6-phosphatase, G6pc), cytochrome p450 metabolism (Cyp4a-10 and -14), FA transport (Cd36; FA binding protein, Fabp5), cholesterol metabolism and transport (apolipoprotein A4, Apoa4; apolipoprotein B-100, ApoB-100), and ketone body formation (mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme A synthase 2, Hmgcs2).


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