Example sentences for: dermal

How can you use “dermal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • reduction of tension in the ECM provokes apoptosis and reduces α-SMA; as human dermal myofibroblasts readily undergo apoptosis in response to gel relaxation (or wound contraction) their absence from the neodermis of a healed wound is likely the result of apoptosis.

  • We have focused on the effects of the leading Topo I inhibitor, CPT, on collagen production by dermal fibroblasts obtained from patients with SSc.

  • Due to the problem of cell death (>80%) in serum-free medium, cell cycle synchronization of the dermal fibroblasts in serum-free medium was not performed prior to 3H-thymidine assays.

  • Progression of granulation tissue to neodermis requires a decrease in cellularity through apoptosis of endothelial cells, fibroblasts and myofibroblasts [ 28 29 ] . Keloid fibroblasts demonstrate aberrant apoptotic behavior [ 30 31 ] although studies have given variable results [ 5 9 11 30 31 32 33 34 35 ] . Our initial data for serum-starvation-induced apoptosis in monolayer cultures of dermal fibroblasts demonstrated delayed apoptosis of keloid fibroblasts and a negative correlation with α-SMA expression [ 36 ] . Similar correlations were observed in rat lung fibroblasts, where TGFβ1 increased α-SMA content while acting as an antiapoptotic agent [ 37 38 ] . It should be noted however, that many of the myofibroblasts were still able to undergo apoptosis consistent with in vivo data on palatal wound healing [ 39 ] . Thus, TGFβ1 can promote both α-SMA expression in the initial stages of wound healing and apoptosis in later stages of wound healing.

  • Langerhans cell precursors arise from CD34 positive monocytes/macrophages in the marrow [ 33 34 ] . They circulate in the blood before localizing in the skin, primarily in dermal connective tissue.


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