Words similar to depolarizing
Example sentences for: depolarizing
How can you use “depolarizing” in a sentence? Here are some example sentences to help you improve your vocabulary:
To measure inactivation, cells were held at -80 mV, then stepped to a series of depolarizing (pre-pulse) voltages, from -70 mV to +70 mV in 10 mV increments, for 2.5 seconds to promote inactivation, then stepped to -50 mV for 100 ms to close non-inactivated channels, then stepped for 200 ms to the test potential of +20 mV to measure Ca 2+currents, then stepped to the -80 mV holding potential for 5 seconds to permit recovery from inactivation.
Absence of the γ 1 subunit slows inactivation and produces a depolarizing shift in the Ca 2+current inactivation vs. voltage curve, in agreement with results from an independently produced γ 1 knockout mouse [ 20].
Whole-cell patch clamp currents recorded from a PGC-2 cell, in response to a series of six depolarizing test pulses of 1 s duration (step +20 mV) from a holding potential of -50 mV, before (left) and after (middle) application of 2 mM 4-aminopyridine (4-AP).
For post-tetanic γ oscillations, the slow depolarizations were mediated by tetanic stimulation-induced GABAergic depolarizing action [ 20 21 22 23 ] . This GABAergic depolarization is attributed to the tetanic stimulation-induced accumulation of intracellular chloride [ 24 ] and extracellular potassium [ 22 ] . For hyperthermic γ oscillations, heating causes a Na +/K +pump failure [ 8 ] , in turn resulting in the accumulation of intracellular Na +and Cl -, as well as extracellular K +, finally causing a slow membrane depolarization.
Cells were held at -80 mV, then stepped to a series of depolarizing (pre-pulse) voltages for 2.5 s to promote inactivation, then stepped to -50 mV for 100 ms to close non-inactivated channels.
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