Words similar to depolarizing
Example sentences for: depolarizing
How can you use “depolarizing” in a sentence? Here are some example sentences to help you improve your vocabulary:
2Ashows whole-cell Ca 2+currents in control, γ 1 het and γ 1 null myotubes in response to 500-ms depolarizing voltage steps from a holding potential of -40 mV.
We have shown previously that antagonism of the slowly activating non-inactivating granulosa K +current (I Ks ) enhances basal progesterone production by depolarizing membrane potential and thus enhancing calcium influx via pimozide-sensitive Ca 2+channels [ 18 ] . In contrast, Kusaka [ 21 ] showed that antagonism of 4-AP sensitive slowly inactivating delayed rectifier K +currents suppressed both basal and LH-stimulated progesterone production.
To measure inactivation, cells were held at -80 mV, then stepped to a series of depolarizing (pre-pulse) voltages, from -70 mV to +70 mV in 10 mV increments, for 2.5 seconds to promote inactivation, then stepped to -50 mV for 100 ms to close non-inactivated channels, then stepped for 200 ms to the test potential of +20 mV to measure Ca 2+currents, then stepped to the -80 mV holding potential for 5 seconds to permit recovery from inactivation.
Cells were held at -80 mV, then stepped to a series of depolarizing (pre-pulse) voltages for 2.5 s to promote inactivation, then stepped to -50 mV for 100 ms to close non-inactivated channels.
Whole-cell patch clamp currents recorded from a PGC-2 cell, in response to a series of six depolarizing test pulses of 1 s duration (step +20 mV) from a holding potential of -50 mV, before (left) and after (middle) application of 2 mM 4-aminopyridine (4-AP).
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