Example sentences for: depolarizing

How can you use “depolarizing” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We have shown previously that antagonism of the slowly activating non-inactivating granulosa K +current (I Ks ) enhances basal progesterone production by depolarizing membrane potential and thus enhancing calcium influx via pimozide-sensitive Ca 2+channels [ 18 ] . In contrast, Kusaka [ 21 ] showed that antagonism of 4-AP sensitive slowly inactivating delayed rectifier K +currents suppressed both basal and LH-stimulated progesterone production.

  • Cells were held at -80 mV, then stepped to a series of depolarizing (pre-pulse) voltages for 2.5 s to promote inactivation, then stepped to -50 mV for 100 ms to close non-inactivated channels.

  • 2Ashows whole-cell Ca 2+currents in control, γ 1 het and γ 1 null myotubes in response to 500-ms depolarizing voltage steps from a holding potential of -40 mV.

  • Moreover, increasing the abundance of TRPC3 in cultured myotubes prolongs the period in which intracellular calcium is elevated following a depolarizing stimulus, sustains the transcription factor NFAT within the nucleus, and augments expression of NFAT-dependent target genes [40].

  • Insulin treatment did not affect the general characteristics of the Cl -current induced by 5-HT or Ach, i.e., a depolarizing current with a rapid transient peak and slower oscillatory phase (Figs.


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