Example sentences for: depolarizing

How can you use “depolarizing” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Insulin treatment did not affect the general characteristics of the Cl -current induced by 5-HT or Ach, i.e., a depolarizing current with a rapid transient peak and slower oscillatory phase (Figs.

  • Whole-cell patch clamp currents recorded from a PGC-2 cell, in response to a series of six depolarizing test pulses of 1 s duration (step +20 mV) from a holding potential of -50 mV, before (left) and after (middle) application of 2 mM 4-aminopyridine (4-AP).

  • For post-tetanic γ oscillations, the slow depolarizations were mediated by tetanic stimulation-induced GABAergic depolarizing action [ 20 21 22 23 ] . This GABAergic depolarization is attributed to the tetanic stimulation-induced accumulation of intracellular chloride [ 24 ] and extracellular potassium [ 22 ] . For hyperthermic γ oscillations, heating causes a Na +/K +pump failure [ 8 ] , in turn resulting in the accumulation of intracellular Na +and Cl -, as well as extracellular K +, finally causing a slow membrane depolarization.

  • The results obtained here in skeletal muscle demonstrate that absence of the γ 1 subunit increases Ca 2+current density, decreases the inactivation rate, and shifts the voltage-dependence of inactivation in the depolarizing direction.

  • Current generated by the active population travels through the resistances of the extracellular space and of the nearby inactive cells, therefore producing the extracellular population spikes and meanwhile depolarizing the inactive cells.


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