Example sentences for: depolarizing

How can you use “depolarizing” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The results obtained here in skeletal muscle demonstrate that absence of the γ 1 subunit increases Ca 2+current density, decreases the inactivation rate, and shifts the voltage-dependence of inactivation in the depolarizing direction.

  • Absence of ICa 2+was further verified using longer 500-ms depolarizing pulses (not shown).

  • 2Ashows whole-cell Ca 2+currents in control, γ 1 het and γ 1 null myotubes in response to 500-ms depolarizing voltage steps from a holding potential of -40 mV.

  • Cells were held at -80 mV, then stepped to a series of depolarizing (pre-pulse) voltages for 2.5 s to promote inactivation, then stepped to -50 mV for 100 ms to close non-inactivated channels.

  • To measure inactivation, cells were held at -80 mV, then stepped to a series of depolarizing (pre-pulse) voltages, from -70 mV to +70 mV in 10 mV increments, for 2.5 seconds to promote inactivation, then stepped to -50 mV for 100 ms to close non-inactivated channels, then stepped for 200 ms to the test potential of +20 mV to measure Ca 2+currents, then stepped to the -80 mV holding potential for 5 seconds to permit recovery from inactivation.


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