Example sentences for: depolarization

How can you use “depolarization” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For post-tetanic γ oscillations, the slow depolarizations were mediated by tetanic stimulation-induced GABAergic depolarizing action [ 20 21 22 23 ] . This GABAergic depolarization is attributed to the tetanic stimulation-induced accumulation of intracellular chloride [ 24 ] and extracellular potassium [ 22 ] . For hyperthermic γ oscillations, heating causes a Na +/K +pump failure [ 8 ] , in turn resulting in the accumulation of intracellular Na +and Cl -, as well as extracellular K +, finally causing a slow membrane depolarization.

  • Increase in cytosolic Ca 2+started at the onset of the depolarization and peaked ∼ 100 ms later in the three cell types.

  • To describe the possible effects of membrane potential and ion fluxes on cellular activity in Figure 5, we have introduced an electrical 'voltage' property (represented by the 'depol' (depolarization) process icon) of membrane-bound compartments and an ionic 'charge' property used to derive 'ion' icons from atom icons.

  • Chloride channels or chloride ions are known to influence cAMP-stimulated steroidogenesis by adrenal cells [ 29 ] , human chorionic gonadotropin (hCG)-stimulated steroidogenesis by amphibian follicle-enclosed oocytes [ 56 ] , as well as LH-stimulated steroidogenesis in rat Leydig cells [ 29 ] , MA-10 cells [ 59 ] , and chicken GC [ 35 ] . In mammalian cells, removal of extracellular chloride stimulates basal and protein kinase A (PKA)-dependent steroid hormone production by increasing the expression of StAR and potentiating the effects of submaximal concentrations of cAMP [ 29 59 ] . The proposed mechanism of action involves chloride efflux, depolarization of the mitochondrial and plasma membranes, and alterations to protein synthesis and cholesterol transport [ 29 59 ] .

  • Secondly, muscimol might increase the chloride conductance independent of gap junctions, and might cause a decrease in the spread of depolarization.


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