Words similar to depletion
Example sentences for: depletion
How can you use “depletion” in a sentence? Here are some example sentences to help you improve your vocabulary:
Our data is consistent with that of Fluckiger et al [ 8], who proposed that Btk controls BCR-induced calcium signaling by regulating PLCγ2 activation, IP3 levels and calcium store depletion.
First, why is it that early antiretroviral treatment, even if it does lead to better control of viral replication, does not protect against CD4+ T cell depletion?
Capsaicin's use in the treatment of chronic pain is due to an analgesic effect that is explained by capsaicin's action of depletion of stores of substance P from primary sensory neurons as a consequence of the reduced production of prostaglandin [ 39 60 ] . Capsaicin's antiphlogistic activity is due to the "counter-irritant effect"; which means that a local irritant effect exerts an additional more remote antiinflammatory effect [ 60 ] . This is explained by a liberation of corticoids under the influence of certain cutivisceral reflexes [ 60 ] . The counter-irritant effect on the gastric mucosa also occurs because capsaicin stimulates production of the cytoprotective prostaglandin E 2 [ 60 ] . Capsaicin produces analgesic and antiinflammatory effects because it inhibits both 5-lipoxygenase and cycoloxygenase [ 39 ] . A 10 g human ingestion of red pepper stimulated carbohydrate oxidation [ 62 ] . This may explain why the Chocó Indians used it to give their hunting dogs more "energy" [ 25 ] .
CO may also be decreased in adrenal insufficiency as the result of the myofibrillar adenosine triphosphate (ATP) depletion seen with glucocorticoid deficiency [ 20].
However before this picture about the involvement of NK cells in LAK activity emerged there existed considerable controversy regarding the type of effector cells mediating this activity, particularly concerning the relative contributions by the two lymphocyte populations, NK Vs cytotoxic T cells [ 5 6 7 8 9 ] . Experiments in which, depletion of Asialo-GM (a glycolipid present on the surface of NK cells) was carried out, demonstrated, that the generation of LAK cells followed by IL-2 stimulation was considerably reduced, thereby confirming that the NK cells are the major contributors of LAK activity [ 10 ] . Further, studies with sorted pure populations of CD3/NK cells also showed that the LAK phenomenon is predominantly mediated by IL-2 activated NK cells.
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