Example sentences for: depletion

How can you use “depletion” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The hypodynamic state is usually seen early in adrenal insufficiency and is associated with volume depletion from diarrhea, vomiting, and decreased reabsorption of sodium in the distal tubule.

  • The present study was performed to examine the effect of propylthiouracil treatment of patients with plaque psoriasis on CD1a expression in their psoriatic lesions in order to determine whether this form of therapy resulted in depletion of APCs from affected skin, that could account for the therapeutic benefit of PTU in this disorder.

  • As expected, qualitative assessment of images from samples exposed to IL-1 exhibited the characteristic heterogeneity in degree of GAG depletion.

  • The fact that depletion of heparin/HS-like GAGs from the culturing media results in inhibition of PEDF binding to cell surface receptors points to functional roles for these GAGs such as those of positive modulators of PEDF-receptor interactions.

  • Skin antigen-presenting cells (Langerhans cells) appear to play an important role in the initiating events that lead to the cytokine cascade that results in keratinocyte proliferation and development of psoriatic lesions [ 16 17 18 ] . Effective therapeutic approaches to psoriasis treatment, such as psoralen UV-A therapy (PUVA), which result in depletion of APCs in the skin [ 19 20 ] , and UV-B [ 21 ] , lead to one of the most sustained improvement in psoriasis.


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