Example sentences for: depleting

How can you use “depleting” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Looking more generally at attempts to evaluate [GAG] recovery in IL-1-degraded cartilage, our data are consistent with the temporal progression seen in other model systems in which recovery occurs and is measurable within the first few weeks after a [GAG]-depleting intervention.

  • A common feature of the tryptophan depleting clones was their tendency to form macroscopic foci, which were visible to the naked eye (Fig 2,A,B,C).

  • Apoptotic cells were identified by the TdT-mediated dUTP-biotin nick end labeling (TUNEL) method and detected either by flow cytometry [ 27 ] or by light microscopy in histological sections [ 28 ] . The results indicate that transgenic ABP alters the rate of testicular germ cell apoptosis throughout life, but it is most likely to cause its germ-cell depleting effect by promoting germ cell apoptosis during the critical pre-pubertal period ("puberty" in laboratory rodents occurs at 50-60 days of life and is defined as the first appearance of spermatozoa in the tail of the epididymis [ 29 30 ] ).

  • Once in the tissue, monocytes undergo the poorly understood process of transformation to macrophages with altered morphology and function [ 19 ] . In arthritis, synovial macrophages might cause joint destruction by differentiating to bone-resorbing osteoclasts [ 20 ] or by releasing cartilage-degrading enzymes and cytokines, such as interleukin-1 and tumor necrosis factor-α [ 8 ] . It has therefore been suggested that therapies for chronic arthritis should be aimed at depleting joint mononuclear cells or controlling the activation of synovial macrophages [ 21 ] . Indeed, elimination of macrophages by clodronate-laden liposomes in rat models of adjuvant [ 22 ] and antigen-induced arthritis [ 23 ] induces amelioration of the arthritis.

  • The traditional explanation for this association is that, since red is inconspicuous to bees, it evolved to prevent bees from depleting the nectar of bird-pollinated flowers without effecting pollination.


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