Words similar to deneddylation
Example sentences for: deneddylation
How can you use “deneddylation” in a sentence? Here are some example sentences to help you improve your vocabulary:
This mutant accumulates Pcu1p exclusively in a form carrying the stimulatory Nedd8p modification, due to a defect in COP9/signalosome-mediated cullin deneddylation [ 24 25 ] . Replacing wild-type ubiquitin by a mutant lacking all lysine residues prevented the formation of high molecular weight products (Fig.
The results presented here eliminate the attractive hypothesis that the cysteine box in Csn5p, which is conserved in numerous deubiquitylating enzymes [ 23], harbors a critical activity for deneddylation (Fig.
Thus, CSN may exert negative control on Pcu1p and Pcu3p by promoting their deneddylation.
2C, 2D), where both cullins seem constitutively neddylated, argues against a critical role for dynamic cycles of neddylation and deneddylation in cullin function in fission yeast.
So far, we were unable to obtain deneddylation of Pcu3p-13Myc in vitro by partially purified CSN preparations active in deneddylation of Pcu1p-13Myc (data not shown).