Words similar to deneddylation
Example sentences for: deneddylation
How can you use “deneddylation” in a sentence? Here are some example sentences to help you improve your vocabulary:
The conserved "cysteine box" in Csn5p is not required for Pcu3p deneddylation
Our study also provides some insight into the role of deneddylation in cullin function, as we were able to create a situation in which Pcu1p and Pcu3p are fully neddylated in vivo (ref [ 10] and data presented here).
This mutant accumulates Pcu1p exclusively in a form carrying the stimulatory Nedd8p modification, due to a defect in COP9/signalosome-mediated cullin deneddylation [ 24 25 ] . Replacing wild-type ubiquitin by a mutant lacking all lysine residues prevented the formation of high molecular weight products (Fig.
Thus, CSN may exert negative control on Pcu1p and Pcu3p by promoting their deneddylation.
So far, we were unable to obtain deneddylation of Pcu3p-13Myc in vitro by partially purified CSN preparations active in deneddylation of Pcu1p-13Myc (data not shown).
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