Words similar to delg

Example sentences for: delg

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Four cell lines from females with known MECP2 mutations (R106W, R255X, and two with 803delG) but completely skewed X chromosome inactivation with the wild-type MECP2 allele on the active X chromosome were also cultured.
Clonal cell lines with the mutant MECP2 allele on the active X chromosome were derived from lymphoblastoid cell lines (LCLs) from four females with clinically diagnosed Rett syndrome and known mutations (T158M, 803delG, R168X) [ 10 ] and 1159del28 (unpublished) using the technique described above.
Cell clones expressing an allele with a truncating mutation (FB 705delG, FB 1155del32, LCL R168X), do not produce a normal sized MECP2 protein.
The number of genes with increased (+) and decreased (-) levels of expression in mutant MeCP2 over wild-type expressing clones differed among the fibroblast strains studied (R106W: 889+, 3056-; R306C: 1700+, 1435-; 705delG: 1160+, 1240-; 1155del32: 2996+, 1235-).
Expression profiles from the mutant clonal cell line (1159del28) and three additional clonal mutant MeCP2 expressing cell lines (T158M, 803delG, R168X) were compared to the baseline expression profiles.