Words similar to delg

Example sentences for: delg

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Expression profiles from the mutant clonal cell line (1159del28) and three additional clonal mutant MeCP2 expressing cell lines (T158M, 803delG, R168X) were compared to the baseline expression profiles.
For the 20 different comparisons, we included three mutant-allele expressing clones (T158M, 803delG, R168X) and four completely skewed wild-type MeCP2 expressing LCLs (R106W, R255X, 803delG, 803delG) from different donors.
Four cell lines from females with known MECP2 mutations (R106W, R255X, and two with 803delG) but completely skewed X chromosome inactivation with the wild-type MECP2 allele on the active X chromosome were also cultured.
The number of genes with increased (+) and decreased (-) levels of expression in mutant MeCP2 over wild-type expressing clones differed among the fibroblast strains studied (R106W: 889+, 3056-; R306C: 1700+, 1435-; 705delG: 1160+, 1240-; 1155del32: 2996+, 1235-).
Cell clones expressing an allele with a truncating mutation (FB 705delG, FB 1155del32, LCL R168X), do not produce a normal sized MECP2 protein.