Words similar to delg

Example sentences for: delg

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Cell clones expressing an allele with a truncating mutation (FB 705delG, FB 1155del32, LCL R168X), do not produce a normal sized MECP2 protein.
Baseline expression profiles were derived from the clonal wild-type cell line (1159del28), and the four completely skewed wild-type cell line controls (R106W, R255X, 803delG, 803delG).
Expression profiles from the mutant clonal cell line (1159del28) and three additional clonal mutant MeCP2 expressing cell lines (T158M, 803delG, R168X) were compared to the baseline expression profiles.
The number of genes with increased (+) and decreased (-) levels of expression in mutant MeCP2 over wild-type expressing clones differed among the fibroblast strains studied (R106W: 889+, 3056-; R306C: 1700+, 1435-; 705delG: 1160+, 1240-; 1155del32: 2996+, 1235-).
We, therefore, extended the microarray analyses to lymphoblastoid cell lines (LCLs) and studied four clonal mutant MeCP2 (T158M, 803delG, R168X and 1159del28) expressing and one clonal (1159del28) and four completely skewed (R106W, R255X, 803delG, 803delG) wild-type MeCP2 expressing LCLs.