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Example sentences for: defining

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Defining a True Progenitor
Viewing the most defining proteins with altered expression, it is clearly reflective of increased apoptosis (increased Chk1, Caspase 6, E2F1), decreased cell proliferation and branching (decreased GR), and, interestingly, increased expression of diverse signal transduction pathways (Ras/Raf/ERK, JNK) to compensate for the proapoptotic signal.
A longer sequence in the defining set might make a slightly higher-scoring profile by the addition of a few carboxy- or amino-terminal residues, but only at the risk of missing slightly shorter members of the set when the profile is used to search the databases.
The defining structural feature of this domain is seen in the loop between strands 5 and 6 (Figs.
1) transcripts or proteins with altered expression best discriminate CONT from SN50-treated explants with 100% sensitivity and specificity [ 69 ] . PNN analyses identify the relative importance (0-1, with 0 being of no relative importance and 1 being relatively most important) of gene and protein expression changes in defining the SN50 phenotype.