Example sentences for: define

How can you use “define” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The rec12-117 mutant was isolated in a genetic screen; the rec12-117 mutation reportedly confers a 100-fold or greater reduction of intragenic recombination and a 6-fold reduction of intergenic recombination [ 33 ] . To define more precisely the requirement for Rec12 in meiotic chromosome dynamics, we used gene replacement to generate a null ( rec12-D15 ) mutation and a mutation in the putative active site tyrosine ( rec12-Y98F ). We then determined the effects of these mutations upon intergenic (crossover) recombination within intervals of chromosomes

  • A G1 block has been reported previously in C/EBPα-expressing mouse L cells [ 26 ] . However, those studies did not define the activities within C/EBPα required for that blockage.

  • To define the underlying mechanisms by which anti-TNF-α mAb ameliorated joint inflammation and structural damage, the levels of various proinflammatory mediators were examined.

  • Prognostic factors such as tumour size, tumour grading, hormone receptor status, age, histology, ploidy and proliferation index are used to define subgroups of high-risk NNBC patients [ 1 2 3 4 5 6 7 8 ] . Despite the availability of these prognostic markers, high-risk NNBC patients cannot be identified with sufficient accuracy.

  • In an effort to define a novel gene family, we set out to identify genes related to TMC1 , TMC2 , EVER1 , and EVER2 [ 5 6 7 ] . We obtained the coding sequences of additional homologues in human and mouse, which form the TMC protein family (Figures 1, 2).

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