Words similar to deficient

Example sentences for: deficient

How can you use “deficient” in a sentence? Here are some example sentences to help you improve your vocabulary:

IFN-γ levels are reduced in IL-10-deficient mice
Although several laboratories reported that crosslinking CD5 on the surface augments T cells signaling by inducing calcium flux and enhancing mitogenic response [ 14, 15, 16], recent studies using CD5-deficient mice indicate that CD5 may be more important as a negative modulator of TCR and BCR signal transduction [ 17, 18].
This would allow for the iron deficient animal to increase cardiac output through enhanced stroke volume, while maintaining the amount of time available for cardiomyocyte perfusion.
The cells were then washed several times with serum-free media and placed in serum deficient media for 14 hours to prevent GFP-GR translocation to the nucleus, prior to treatment with 500 nM dexamethasone (30 min.) or with vehicle alone.
PTEN is altered or deleted in many human cancers [ 7 8 9 10 ] . In-vitro, cells that are deficient in PTEN show elevated PI-3Kinase signaling [ 11 ] . Reintroduction of PTEN in a variety of cancer cells, including glioma, breast, bladder and ovarian cancer cells, causes G1 arrest, inhibits tumorigenesis, and promotes anoikis [ 12 13 14 ] . Mechanistically, Akt activity is decreased, cell motility is decreased, expression of two cyclin-dependent kinase inhibitors p27 and p21 is increased, cyclin D1 is down-regulated, Rb phosphorylation is inhibited, and signaling via Grb2/SOS is suppressed [ 11 15 ] . The link between PTEN and cell growth is underscored by genetic experiments in mice.