Words similar to dedifferentiation
Example sentences for: dedifferentiation
How can you use “dedifferentiation” in a sentence? Here are some example sentences to help you improve your vocabulary:
Therefore, reversine and Msx1 appear to have a similar effect on mouse myoblasts, although no reports have yet addressed whether reversine might induce dedifferentiation of multinucleated myotubes.
Infection of cultured podocytes with replication incompetent HIV-1 demonstrated that HIV-1 gene expression leads to the proliferation and dedifferentiation of the infected podocytes [ 6 7 8 ] , recapitulating the phenotypes observed in HIVAN specimens [ 9 10 ] . Similarly, renal expression of replication incompetent HIV-1 proviral transgenes in mice and rats produces a proliferative renal lesion that is indistiguisable both histopathologically and clinically from human HIVAN [ 11 12 13 14 ] . These observations raise the possibility that HIV-1 gene products may interact with mitogenic pathways in infected renal epithelium to cause aberrant cell-cycle engagement.
Furthermore, Msx1 may be functioning not only to prevent differentiation of progenitor cells but also to induce dedifferentiation of cells that have already differentiated.
This latter process, known as cellular dedifferentiation, is especially prominent in vertebrates with exceptional regenerative abilities, such as salamanders.
In this way, MEC-3 activates its own transcription, which probably prevents the dedifferentiation of the touch neurons.
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