Words similar to dedifferentiation

Example sentences for: dedifferentiation

How can you use “dedifferentiation” in a sentence? Here are some example sentences to help you improve your vocabulary:

Infection of cultured podocytes with replication incompetent HIV-1 demonstrated that HIV-1 gene expression leads to the proliferation and dedifferentiation of the infected podocytes [ 6 7 8 ] , recapitulating the phenotypes observed in HIVAN specimens [ 9 10 ] . Similarly, renal expression of replication incompetent HIV-1 proviral transgenes in mice and rats produces a proliferative renal lesion that is indistiguisable both histopathologically and clinically from human HIVAN [ 11 12 13 14 ] . These observations raise the possibility that HIV-1 gene products may interact with mitogenic pathways in infected renal epithelium to cause aberrant cell-cycle engagement.
This latter process, known as cellular dedifferentiation, is especially prominent in vertebrates with exceptional regenerative abilities, such as salamanders.
In this way, MEC-3 activates its own transcription, which probably prevents the dedifferentiation of the touch neurons.
Given the high-tech world of modern biology, the method by which the Scottish team managed to provoke this extraordinary dedifferentiation is almost old-fashioned in its simplicity.
Proliferation and dedifferentiation of HIV-1 infected renal epithelium is singularly unique compared to the effects of HIV-1 infection in other non-lymphoid tissues.