Example sentences for: death-inducing

How can you use “death-inducing” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus, although NGF is an effective anti-apoptotic factor, these actions do not appear to be mediated by down-regulation of potentially death-inducing RPs.

  • Recent work has shown that the Bcl-2 family regulates mitochondrial homeostasis during apoptosis [ 1 ] . Pro-apoptotic members, including Bax, Bak, Bid, and Bim, promote the release of death-inducing proteins, such as cytochrome c [ 2 3 ] , smac [ 4 ] , and endonuclease G [ 5 ] , from mitochondria while anti-apoptotic members, such as Bcl-2 and Bcl-X L , inhibit this release.

  • An anti-CD81 antibody was first isolated for its ability to induce cell death in B cell lines [ 11 ] . This is likely dependent upon CD81's association with MHC class II molecules, which can transmit death-inducing signals in B cells [ 12 ] . CD81 cross-linking can also induce adhesion in B and T cells, apparently by multiple pathways [ 10 13 14 ] . Triggering of the CD19-CD21-CD81 complex on murine B cells has been shown to lower the threshold for B cell activation via the immunoglobulin receptor [ 15 ] .

  • Following release into the cytosol, these death-inducing proteins promote apoptotic cell destruction through multiple pathways including caspase activation and nuclear DNA fragmentation.


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