Example sentences for: deactivation

How can you use “deactivation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The cleavage and subsequent deactivation of this caspase 3-dependent DNase inhibitor suggested that amino-terminal BRCA1 mutations enhance cellular apoptosis contributing to poor cell survival.

  • It is thus conceivable to interpret that the profound inhibition in E2F-1 and PCNA protein levels after 24 h of exposure to 2.5 μM SAHA may result in disintegration and deactivation of D1, E and A cdk2 complexes, which consequently leads to hypophosphorylation of the three Rb pocket proteins.

  • The data demonstrate that PGC-2 cells express K +currents similar to the granulosa cell ultra-rapid delayed rectifier current (I Kur ) in terms of the voltage-dependence and kinetics of activation and deactivation, as well as the sensitivity to 4-AP.

  • These data suggest a biphasic response with ser 16-HSP20 phosphorylation-associated force suppression with heat pretreatment between 43 and 46°C and deactivation by inhibition of ser 19-MRLC phosphorylation after heat pretreatment at 47.

  • Cyclic nucleotide induced relaxation is associated with phosphorylation of heat shock protein 20 (also known as HSP20 or P20) on serine 16 [ 10 11 12 ] . More recently, ser 16-HSP20 phosphorylation was shown to specifically and temporally correlate with "force suppression" rather than the "deactivation" form of relaxation [ 8 10 ] . A region of HSP20 (residues 110-121) has sequence homology with troponin I; peptides from this region bound thin filaments, reduced actin activated myosin S1 ATPase activity, and relaxed skinned swine carotid artery [ 10 ] . We hypothesized that binding of ser 16-phosphorylated HSP20 to the thin filament may "turn off" thin filaments so that phosphorylated myosin does not interact with the thin filament (i.e.


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