Words similar to d-akap
Example sentences for: d-akap
How can you use “d-akap” in a sentence? Here are some example sentences to help you improve your vocabulary:
This suggests to us that anti-D-AKAP1 may be occluding RIα bound to D-AKAP1 to the extent that anti-RIα has little access to its antigen.
A band for RIIβ was detected in contrast to a report of no RIIβ detection in soleus or extensor digitorum longus muscles [ 18 ] , which might be explained by the presence of nerve fibers or adipocytes wherein RIIβ is prevalent [ 27 ] . The blot for the affinity-purified D-AKAP1 antibody is shown because the protein-A purified antibody displayed additional, unexplained bands; however, no difference in fluorescence labeling was observed when using antibodies purified either way.
Because we produced antibodies to two novel dual-specific AKAPs (D-AKAP1 and D-AKAP2), and gravin, we were uniquely positioned to use immunofluorescence to investigate their possible roles in kinase signaling in and around the NMJ.
A previous report using immunofluorescence demonstrated colocalization of RIα with the nicotinic acetylcholine receptor (nAChR) at the NMJ postsynaptic membrane [ 19 ] . We used immunohistochemistry coupled with confocal microscopy to acquire detailed information as to the intracellular localization of D-AKAP1 in the several regions of the NMJ and adjacent intercostal muscle to compare with that of RIα.
The labeling pattern of D-AKAP2 is diffuse in the NMJ, yet localized to the actin region in muscle.