Example sentences for: d-a
How can you use “d-a” in a sentence? Here are some example sentences to help you improve your vocabulary:
Pituitary cells that had been re-trypsinized 72 h after infection and then replated (100,000 cells/well in a 24-well poly-L-lysine coated plate) for a 2 h preincubation were subsequently treated with a GnRH agonist (1 ml of 10 -7M D-Ala 6- des Gly 10- GnRH ethylamide; GnRH-A, Sigma, St. Louis, MO) or a calcium ionophore (A23187, Sigma) for 3 h as described by Conn et al.
These are dopamine (DA) receptor agonists, MAO-B inhibitors, and N-Methyl-D-Aspartate (NMDA) receptor antagonists [ 4 ] .
Streptococcus mutans in which DCP is inactive do not initiate growth at below pH 6.5 and make glycerol LTA without D-alanine [ 14 ] . In the DCP active strains, soluble D-Alanyl LTA is extruded into culture fluid in vitro [ 16 17 ] or plaque in vivo [ 18 ] . The D-alanyl esters are stable at pH 6.0 at 37°C, but hydrolyze to free D-alanine and LTA with a half-life of 3.9 h at pH 8.0 [ 19 ] . Healthy gingival sulci have a pH of 6.5 - 7.5 and inflamed sulci a pH of 7.5-8.
These motifs are replaced by others in the S6 modification enzymes and in D-Ala-D-Ala ligases (data not shown), while the motifs involved in the ATP-binding site (1, 4, 6 and 5) are conserved.
The carboxy-terminal parts of these proteins are most closely related to cyanophycin synthetase, which catalyzes the synthesis of a polypeptide storage polymer in cyanobacteria, and more distantly related to D-Ala-D-Ala ligase, which is involved in peptidoglycan biosynthesis in many bacteria.
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