Example sentences for: cytokines

How can you use “cytokines” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Indeed, cytokines have been shown to play an important part in the HIV-1 life cycle and the results obtained here suggest that treatment of PBMCs with HIV-1 envelope proteins significantly modulates the transcription of numerous cytokine genes.

  • The composition of the matrix, the availability of cytokines and proteases, and the expression of various receptors in a given cellular environment might explain these opposing functions.

  • While most cytokine research has focused on cells of the immune system, other cell types produce cytokines including the epithelial cells of the lung [ 28 29 ] , retina [ 30 ] , and intestines [ 31 32 ] . Among the few studies involving the biliary system, it was demonstrated that cultured human intrahepatic duct epithelial cells produce functional IL-8 and MCP-1 (CCL2) [ 14 33 ] . Isolated human intrahepatic epithelial ducts expressed immunoreactive IL-6 when treated with IL-1β or phorbal myristate acetate [ 34 ] . Intracellular TNF-α mRNA and protein was detected in intrahepatic biliary duct cells in tissue sections [ 35 ] , but not in cultured intrahepatic epithelial cells; therefore, there was no clear demonstration that biliary epithelium secretes TNF-α.

  • However, intracellular cytokine analysis proved to be a more sensitive method for detecting cytokines, such as IL-2 and IL-4, and also made it possible to determine the percentage of cells producing each.

  • The addition of SRL significantly decreased the circulating levels of pro-inflammatory cytokines and conversely increased the circulating levels of TGF-β, partially explaining the increased immunosuppression in these patients.


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