Example sentences for: cytokines

How can you use “cytokines” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus, in both species, adipose tissue is an endocrine organ containing adipocytes as well as macrophages that regulates energy metabolism and glucose homeostasis through secretion of multiple factors, including inflammatory cytokines [46].

  • Injection of antigen encoding plasmids can be combined with either adjuvants or plasmids encoding immune enhancing cytokines.

  • In type 1 diabetes, it has been shown that inflammatory cytokines play a central role in the destruction of insulin producing β-cells [ 17 18 19 ] , resulting in the production of oxygen-derived free radicals that induce DNA-damage and apoptosis in both rodent and human β-cells [ 20 21 22 23 24 25 ] . In both type 1 and type 1, as well as, type 2 diabetes, the role of free radicals in diabetic complications is well studied.

  • This change may have been mediated by other cytokines (IL-1β, IL-8) whose levels have been shown to increase with kinetics that parallel this rise in TTP [ 40 46 47 ] . Alternatively, the late rise in cytoplasmic TTP may be due to release from the bone marrow of leukocytes that have high levels of TTP or an adaptive response to endotoxemia.

  • Although MHCII are not expressed by the vast majority of studied mouse and human tumors, CD4+ T lymphocytes specific to MHCII-restricted tumor antigens have been found in various cancers [ 1 ] . Those lymphocytes are believed to be generated in vivo following the recognition of MHCII-tumor peptide complexes expressed by host antigen presenting cells and can cause regression of MHCII-negative tumors indirectly, via secretion of cytokines such as IL-2 or IFNg [ 2 ] . The released cytokines can recruit and activate cytotoxic CD8+ T lymphocytes and/or accessory cells (eosinophills, macrophages) which further mediate tumor destruction.


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