Words similar to cytokines
Example sentences for: cytokines
How can you use “cytokines” in a sentence? Here are some example sentences to help you improve your vocabulary:
Experimental arthritis models have contributed to the basic understanding of joint disease and to the development of effective antiarthritic agents [ 19 ] . Several models have been used to mimic human RA, ranging from immunization with cartilage components to infection with joint trophic organisms [ 20 21 ] . Blocking TNF-α [ 6 22 ] or IL-1 [ 23 24 ] in these models has routinely shown benefit, although some questions remain regarding the role of these cytokines in mitigating joint inflammation versus preventing cartilage degradation and bone erosion [ 25 ] .
Under these conditions apoptosis may result from the production of cytokines [ 1 ] , cell activation [ 2 3 4 ] , infective agents [ 5 ] and adverse responses to pharmaceuticals [ 6 7 ] . Depending on the agonist or eliciting milieu, apoptotic cell death is accompanied by the activation of various cell death pathways including caspases, ceramide, altered gene expression, mitochondrial dysfunction and consumption of ATP e.g., with DNA repair, that result in histone-associated DNA fragmentation [ 8 9 ] . Many of these cell death pathways are also associated with the secondary production of oxidants [ 10 ] which appears to contribute to the magnitude of cell death.
Making incisions into the rabbits may have caused an increase in pro-inflammatory cytokines.
These results imply that, in the synovium, regulation of IFN-γ and LT-α must vary in individual cells, even though both Th1 cytokines can be produced.
NFκB is a ubiquitous transcription factor involved in regulating inflammatory responses, and its targets include several of the genes encoding cytokines and chemokines.
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