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Example sentences for: cyth
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We named this domain the CYTH ( Cy aB, th iamine triphosphatase) domain after the two experimentally characterized proteins in which it is present.
One possibility is that the CYTH domains utilize polyphosphates to synthesize different organo-phosphate derivatives including nucleotides.
Finally, at least in some lineages, the CYTH domain proteins may have been secondarily recruited for other functions.
Classic adenylyl and guanylyl cyclases show a far more sporadic distribution, and are often present in multiple copies fused to a variety of signaling domains such as the cyclic nucleotide binding domains [ 24 ] . Cyclic nucleotide generating activity is not known to exist in a subset of the archaea [ 25 ] , though most of them contain a well-conserved copy of the CYTH domain.
The presence of around 6 conserved acidic positions in the majority of the CYTH domains suggests that it coordinates two divalent metal ions.