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Example sentences for: cyth

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Both domain architecture and operon analysis have been used extensively to make functional predictions of poorly characterized domains or genes [ 26 27 28 29 ] . Moreover, the presence of evolutionarily conserved operons often correlates with the involvement of the component genes in a sequential pathway or physically interacting complex [ 30 31 ] . We summarize the different forms of contextual information that we extracted from the CYTH domains in the form a network diagram (Fig.
The phyletic pattern of the CYTH domain is not very typical of signaling enzymes like nucleotide cyclases.
Genes for CYTH domains also co-occur in predicted operons with genes for another polyphosphate utilizing enzyme, the polyphosphate-dependent NAD kinase (PPNK), in certain cyanobacteria (eg.
The conservation of these two sets of residues in the majority of CYTH domains suggests that most members of this group are likely to possess an activity dependent on two metal ions, with a preference for nucleotides or related phosphate-moiety-bearing substrates.
The possibility of lateral transfer of Aeromonas CyaB from an archaeal source has been previously suggested, and is consistent with the enzyme being optimally functional under high temperature [ 16 ] . There are 3 distinct CYTH domains in the euryarchaeon Methanosarcina acetivorans , in addition to the version which groups with the CYTH domains that are found, in single or duplicate copies, in other archaea and eukaryotes.